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Posted by alfachemistry on December 11th Wholesale Jerseys From China , 2018


Because people often come into contact with the outside world, normal breathing, external pollution and radiation exposure can cause free radicals in the human body. Excessive free radicals can cause aging or other diseases of the human body, and free radical antioxidants can effectively overcome these hazards. Therefore, antioxidant has become one of the main research topics in the health care products and cosmetics market. Different plant extracts have different active ingredients. Similarly, plant extracts with antioxidant effects also have many different components, and their mechanism of action is also different. This article describes the antioxidative mechanism of plant extracts.


1 Acting on free radical-related enzymes


The enzymes related to free radicals are divided into two types: oxidase and antioxidant enzymes. The antioxidant activity of plant extracts is reflected in the inhibition of the activities of related oxidases and the enhancement of antioxidant enzyme activities.


1.1 Inhibition of oxidase activity


There are many oxidases in the organism Wholesale Jerseys China , such as P-450 enzyme, xanthine oxidase (XOD), lipoxygenase, myeloperoxidase(MPO) and cyclooxygenase, which are related to the generation of free radicals. Studies have shown that many plant extracts have inhibitory effects on various oxidases described above, inhibiting free radical generation from the source. For example, quercetin and curcumin in flavonoids can inhibit the activity of iNOS during ischemia-reperfusion injury Wholesale Jerseys , thereby exerting an antioxidant effect.


1.2 Enhancement of antioxidant enzyme activity


The body has antioxidant enzymes that can remove and repair excess free radicals, such as catalase (CAT), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and peroxidase and the like. Many studies have shown that antioxidants in plant extracts not only protect antioxidant enzymes in the body, but also enhance the activity of antioxidant enzymes in the body. For example, quercetin in flavonoids can reduce the oxidative damage of islet β cells http://www.wholesalemlbjerseysforcheap.com/ , and it can also restore the activity of SOD, GSH-Px and CAT in animals with Fe2+-induced renal cell injury. Saponins have little effect on oxygen free radicals, but most of them can increase the activity of antioxidant enzymes such as SOD and CAT in vivo, thus enhancing the anti-oxidation function of body.


2 Complementarity and synergy between antioxidant components


There is a complementary and synergetic relationship between the antioxidant components of plant extracts, which exert antioxidant effects by transferring electrons andor protons in the human body, acting on oxidases and antioxidant enzymes, chelating and inactivating transition metal ions. Study have found that there were significant synergistic effects between different concentrations of tea polyphenols and American ginseng Cheap Baseball Jerseys , and the synergistic effects increased with the increase of concentrations.


3 Direct removal or inhibition of free radicals