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NEW YORK -- Grady Sizemores big hit against an old friend ensured Jon Lester finally had something to show for an impressive effort. Sizemore hit a three-run homer in the sixth inning off CC Sabathia and the Boston Red Sox gave Lester enough run support for his first win of the year, 4-2 over the New York Yankees on Friday night. "Good to have a rally there in that inning," Sizemore said. "Weve kind of struggled with Jon on the mound. Its nice to pick him up and get some runs for him." It wasnt all positive news for Boston in its first win this season over the rival Yankees. Closer Koji Uehara was held out of the game because he had some right shoulder stiffness when throwing during pregame warmups. Manager John Farrell used Edward Mujica in the ninth instead of the 39-year Uehara as a precaution. "We felt it was best to stay away from him," Farrell said. "Itll be a day-to-day thing." Jonny Gomes led off the sixth with another long ball off Sabathia, and the four-run inning was more runs than Boston had scored for Lester in his first two starts combined (one). Despite a 2.51 ERA coming in, Lester was at risk of falling to 0-3 for the first time in his big league career. The left-hander was lifted with two outs in the seventh after Kelly Johnson singled to pull the Yankees within two runs, his first hit in 15 career at-bats against Lester (1-2). Junichi Tazawa relieved with runners at the corners and retired Derek Jeter on a flyout. Jeter hit leadoff for the Yankees for first time since breaking his left ankle in the 2012 AL championship series opener. He beat out an infield single in four at-bats. Lester allowed Alfonso Sorianos homer starting the second and six hits overall. He walked two and struck out six in improving to 12-5 in 27 starts against New York. "I dont feel like I threw the ball as well the first two, but sometimes you need games like this to appreciate the ones where you glide through," Lester said. "This was a little bit of a grinder." Tazawa pitched 1 1-3 innings of one-hit relief, and Mujica was perfect in the ninth for his first save with Boston. "Im ready to go whatever the situation," said Mujica, who had 37 saves for St. Louis and made the NL All-Star team last year before losing his closers job in September. Sabathia (1-2) pitched without the controversy that surrounded teammate Michael Pineda in a series-opening 4-1 win Thursday but also without the success. Pineda gave up one run and four hits in six-plus innings but was caught on camera with a brown substance on his hand. Joe Torre, Major League Baseballs executive vice-president for baseball operations, said in a statement Friday that Pineda will not be suspended. Looking as if he was setting aside talk of being an ace on the decline, Sabathia was dominant for five innings. He allowed just David Ross third-inning double until Gomes led off the sixth with his first homer of the year, on an 89 mph four-seam fastball. Four batters later, Sizemore crushed an 80 mph slider into right field for a 4-1 lead. The duo were teammates in Cleveland before Sabathia was traded to Milwaukee during the 2008 season. "You go out and compete, even against friends," Sabathia said. "Tonight he got the best of me." Sabathias fastball velocity has declined from 94.1 mph in 2009, his first season in New York, to 89.7 mph this year entering Friday. Last year he gave up 45 of his major league-leading 122 runs on a career-high 28 homers allowed. Hes already yielded five this season. Sabathia allowed four runs and six hits in seven innings, striking out nine and walking two. Hes given up at least four runs in each of his three starts and has a 6.63 ERA. ""I was a little bit better," Sabathia said. "I havent really been able to put a whole game together." NOTES: Former Red Sox Jacoby Ellsbury and Matt Thornton were given their World Series rings in a meeting with Boston GM Ben Cherington and Farrell before the game. ... Yankees manager Joe Girardi said 1B Mark Teixeira (right hamstring) should be off the disabled list before May 1 but SS Brendan Ryan (back) is doubtful for the beginning of next month. ... Red Sox OF Shane Victorino took BP and did some light running. Farrell says hell have an idea about a rehab assignment for Victorino after the White Sox series early next week. ... Next up: Bostons John Lackey (2-0) faces New Yorks Hiroki Kuroda (1-1). Cheap Canucks Jerseys . TSN Hockey Insider Bob McKenzie tweeted that its believed the Flames are working towards a new contract with the defenceman. Cheap Canucks Jerseys China . Dillon Brooks scored 26 points on 9-17 shooting for Canada while pulling down six rebounds and picking up six steals. Teammate Chris Egi had 20 points, 14 rebounds and four blocks. http://www.cheapcanucksjerseys.com/ . "Im proud of him," Jones said in an interview from Sacramento, site of the UFCs weekend televised card. "I think hes listening to his body and hes doing what makes him happy and thats what life is about ultimately. Cheap Canucks Jerseys Authentic . The Brad Jacobs team from Sault Ste. Marie, Ont., advanced to Fridays championship game with a 10-6 win over Chinas Rui Liu in the semifinal. 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